Dissolution Paddles Shafts

In the pharmaceutical industry, dissolution paddles play a crucial role in the dissolution testing process, which is essential for ensuring the quality and efficacy of drug formulations. These paddles are attached vertically at the end of a rotating shaft and are used to release the active pharmaceutical ingredient from the dosage form inside the holding vessel.

Materials and Design

Dissolution paddles are available in various materials to suit different sample matrices and testing requirements. Common materials include:

• Electropolished 316 Stainless Steel (SS): Known for its durability and resistance to corrosion. These paddles have a smooth surface that minimizes contamination and ensures consistent results.
• PTFE Coated over 316 SS: Provides additional resistance to chemical reactions and ensures the integrity of the paddle during testing.
• Solid Molded Fluoropolymer: Offers excellent chemical resistance and durability, suitable for a wide range of dissolution media.

Dissolution Paddles Key Features

• Serialized and Compliant: All dissolution paddles are individually serialized, ensuring traceability and compliance with industry standards such as USP (United States Pharmacopeia). Each paddle comes with a Certificate of Conformance (CoC) as standard.

• Variety of Sizes: Paddles are available in multiple sizes to accommodate different vessel volumes, including 100/200 mL, 250 mL, 1L, and 2L. This ensures compatibility with various dissolution apparatus and testing protocols.

• Interchangeable Designs: The two-piece spin on/off shaft design, combined with a fixed installed upper receptor shaft, enables quick and easy interchange between dissolution paddles and basket shafts. This design eliminates the need for lengthy shaft length verification processes.

Applications

These dissolution paddles are compatible with both apparatus 2 and apparatus 5 methods. They are designed to meet the rigorous demands of dissolution testing in pharmaceutical laboratories. The precision tooling of the paddles ensures consistent spin and minimal wobble, which is critical for achieving reliable and reproducible test results.

Key Products:

Product Name	Product Description	Product Link
PAD-13-3590	14.5” (370mm) Paddle for V-Series, Electropolished 316 SS, Serialized	Buy Now
PAD-12-1030	15” (380mm) Paddle, Electropolished 316 SS, Serialized	Buy Now
PAD-12-1040	15” (380mm) Paddle, Electropolished 316 SS, Serialized	Buy Now
PAD-12-1030	21” (535mm) Paddle, Electropolished 316 SS, Serialized	Buy Now
PAD-13-3597	24” (610mm) Paddle, Electropolished 316 SS, Serialized	Buy Now